Leishmaniasis
Developmental genomic changes identified in L. major
Published in TB and Outbreaks Week, August 3rd, 2004
"To complete its life cycle, protozoan parasites of the genus Leishmania undergo at least three major developmental transitions," parasitologists in St. Louis explained. "However, previous efforts to identify genes showing stage-regulated changes in transcript abundance have yielded relatively few."
In their study, N.S. Akopyants and colleagues at Washington University "used expression profiling to assess changes in transcript abundance in three stages: replicating promastigotes and infective non-replicating metacyclics, which occur in the sand fly vector,...
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