HIV/AIDS Opportunistic Infection
Fungal pheromone receptor PCSTE3 from P. carinii cloned and characterized
Published in TB and Outbreaks Week, August 31st, 2004
"The fungal pathogen Pneumocystis carinii remains the most prevalent opportunistic infection in patients infected with HIV.
"Fungal pheromone receptors are seven transmembrane domain G-protein-coupled receptors which are expressed on specific mating types, and have ligand-binding extracellular domains for specific pheromones from cells of the opposite mating type," scientists in the United States report.
"We have cloned and characterized PCSTE3 from P. carinii, which encodes a seven transmembrane domain protein...
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