Published in TB and Outbreaks Week, September 21st, 2004
While "screening new drugs for tuberculosis," scientists in India "identified N1-(4-acetamido phenyl)-N4-(2-nitro benzylidene) semicarbazone (1b)."
This agent strongly "inhibited in vitro Mycobacterium tuberculosis H37 Rv," with "100% inhibition at 1.56 mcg/mL," reported D. Sriram and colleagues working at the Birla Institute of Technology and Science in Rajasthan.
"This paper is first of its kind in which aryl semicarbazones are reported to possess antimycobacterial potency greater than p-aminosalicylic acid,...
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