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Vaccine Safety

Human exposure to raccoon pox vaccine vector leads to limited infection

Published in TB and Outbreaks Week, October 5th, 2004

Human exposure to a recombinant raccoon pox vaccine vector resulted in limited infection.

According to a study from the United States, "A laboratory accident resulted in human exposure to a recombinant raccoon poxvirus (RCN) developed as a vaccine vector for antigens of Yersinia pestis for protection of wild rodents (and other animals) against plague. Within 9 days, the patient developed a small blister that healed within 4 weeks. Raccoon poxvirus was cultured from the lesion, and the patient developed antibody to plague antigen (171) and RCN."

"This is the first documented case of human exposure to recombinant raccoon poxvirus," wrote Tonie...

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