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Hemorrhagic Fever

Ngari virus associated with outbreaks of hemorrhagic fever in Africa

Published in TB and Outbreaks Week, October 12th, 2004

Ngari virus is a Bunyamwera virus reassortant associated with large outbreaks of hemorrhagic fever in Africa.

"Two isolates of a virus of the genus Orthobunyavirus (family Bunyaviridae) were obtained from hemorrhagic fever cases during a large disease outbreak in East Africa in 1997 and 1998. Sequence analysis of regions of the three genomic RNA segments of the virus (provisionally referred to as Garissa virus) suggested that it was a genetic reassortant virus with S and L segments derived from Bunyamwera virus but an M segment from an unidentified virus of the genus Orthobunyavirus," scientists in the United States report.

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