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Hepatitis C Virus Infection

Persistence of hepatitis C virus associated with human leukocyte antigen class 1

Published in TB and Outbreaks Week, November 2nd, 2004

Persistence of hepatitis C virus is associated with human leukocyte antigen class 1.

According to recent research published in the journal Human Immunology, "The aim of this study was to define novel associations between human leukocyte antigen (HLA) class 1 alleles and persistence or clearance of the hepatitis C virus (HCV) in a white population.

"All individuals in the study were seropositive for anti-HCV antibodies. Viral status was determined by the Roche HCV Amplicor test. HLA-A, -B, -C allelic group profile was molecularly defined by reverse line probe hybridization."

"The strongest individual allelic group...

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