AIDS/HIV Diagnosis
HIV-1 superinfections assessed by autologous heteroduplex mobility
Published in TB and Outbreaks Week, November 2nd, 2004
In a recently published article, scientists in France and Burkina Faso conducted a study "to describe and evaluate a simple procedure to identify HIV-1 co- or super-infections based on a heteroduplex mobility assay (HMA). To identify heteroduplexes corresponding to divergent viral populations in a the same individual, HMA was applied to single DNA samples from each subject in a prospective cohort of commercial sex workers (CSW) in Bobo-Dioulasso, Burkina Faso. After denaturation and renaturation of env DNA amplicons,...
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