Published in TB and Outbreaks Week, November 2nd, 2004
The last case of poliomyelitis (polio) in the United States caused by a naturally occurring virus occurred in 1979; however, as a consequence of oral poliovirus vaccine (OPV) use that began in 1961, an average of nine cases of VAPP were confirmed each year from 1961 through 1989.
To reduce the VAPP burden, national vaccination policy changed in 1997 from reliance on OPV to options for a schedule of inactivated poliovirus vaccine (IPV) followed by OPV. In 2000, an exclusive IPV schedule was...
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