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HIV/AIDS-Related Transmission

HIV viral load increases in breast milk following ZDV discontinuation

Published in TB and Outbreaks Week, November 30th, 2004

HIV viral load increases in breast milk following discontinuation of zidovudine.

"Perinatal zidovudine (ZDV) prophylaxis decreases rates of perinatal transmission of human immunodeficiency virus type 1 (HIV-1). Its relationship with levels of HIV-1 RNA in breast milk and postnatal transmission in breast-fed African children is unknown.

"At day 8 after delivery, levels of HIV-1 RNA in breast milk from 28 women who transmitted HIV-1 (Ts) postnatally and from 130 women who did not transmit HIV-1 (NTs) were lower for women receiving ZDV than for women receiving placebo," scientists in France report.

"Levels of HIV-1 RNA in breast milk...

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