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Sepsis

Cells linked to asthma and eczema also help cure deadly illness in mice

Published in TB and Outbreaks Week, December 7th, 2004

Mast cells are immune cells known mostly for their unwanted effects: They cause the wheezing of asthma, the itching of eczema, the sneezing and runny nose of hay fever and, in extreme cases, the life-threatening shock of anaphylaxis.

But researchers at the Stanford University School of Medicine have found that these cells also have some very beneficial effects.

Stephen Galli, MD, the Mary Hewitt Loveless professor and chair of pathology, and his colleagues have shown for the first time that mast cells can provide protection from a potentially deadly condition known as sepsis by destroying a molecule that contributes to the pathology and death...

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