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Environmental Health

Quantum dot system enables photostable Cryptosporidium labeling

Published in TB and Outbreaks Week, December 14th, 2004

A novel quantum dot (QD)-based system enables sensitive and photostable labeling of Cryptosporidium parvum in water.

C. parvum "is a waterborne pathogen that poses potential risk to drinking water consumers," scientists in Singapore explained. "The detection of Cryptosporidium oocysts, its transmissive stage, is used in the latest U.S. Environmental Protection Agency method 1622, which utilizes organic fluorophores such as fluorescein isothiocyanate (FITC) to label the oocysts by conjugation with anti-Cryptosporidium sp. monoclonal antibody (MAb)."

"However, FITC exhibits low resistance to photodegradation," which will...

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