Bacteriology
Role of C. albicans Rim101p in adaptive pH responses clarified
Published in TB and Outbreaks Week, February 8th, 2005
C. albicans "grows and colonizes sites that can vary markedly in pH," scientists in the United States explained. "The pH response in C. albicans is governed in part by the Rim101p pathway."
"In Saccharomyces cerevisiae, Rim101p promotes alkaline responses by repressing expression of NRG1, itself a transcriptional repressor," according to E.S. Bensen and colleagues at the University of Minnesota. In a recent study, they found that, "in C. albicans, Rim101p-mediated alkaline adaptation is not through...
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