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West Nile Virus

West Nile Virus IgM antibodies persist in CSF from patients with CNS disease

Published in TB and Outbreaks Week, February 15th, 2005

West Nile Virus IgM antibodies persist in the cerebrospinal fluid from patients with CNS disease.

"The Michigan Department of Community Health (MDCH) reported 644 laboratory positive human cases of west nile virus (WNV) in the 2002 outbreak in the US, of which 559 cases presented with either meningitis or encephalitis.

"The first line test utilized for diagnosis of WNV infection was the immunoglobulin M (IgM)-capture enzyme-linked immunosorbent assay (MAC-ELISA)," investigators in the United States report.

"We continued testing for WNV even during winter months of the year 2002-2003 due to the awareness of other modes of WNV...

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