Opportunistic Infection

Novel microarray used to characterize genomic variation in C. albicans

Published in TB and Outbreaks Week, April 5th, 2005

A novel single-nucleotide polymorphism (SNP) microarray has been used to characterize genomic variation in Candida albicans.

C. albicans is "a diploid yeast with a predominantly clonal mode of reproduction, and no complete sexual cycle is known," according to scientists in the United States. "As a commensal organism, it inhabits a variety of niches in humans."

"It becomes an opportunistic pathogen in immunocompromised patients and can cause both superficial and disseminated infections," explained A. Forche and colleagues at the University of Minnesota. "It has been demonstrated that genome rearrangement and genetic variation in isolates...

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Source: TB and Outbreaks Week (2005-04-05)

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