Meningococcal Disease
PorA protein relatively stable during meningococcal disease epidemic
Published in TB and Outbreaks Week, April 26th, 2005
According to recent research published in the Journal of Clinical Microbiology, "Meningococci causing New Zealand's epidemic, which began in 1991, are defined as group B, serosubtype P1.4 (subtype P1.7-2,4), belonging to the ST-41/ST-44 complex, lineage III.
"Of the 2,358 group B isolates obtained from disease cases from 1991 through 2003, 85.7% (2,021 of 2,358) were determined to be serosubtype PIA. Of the remaining isolates, 156 (6.6%) were not serosubtypeable (NST)."
"Molecular analysis of the porA gene from these B:NST meningococcal isolates was...
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