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Common Cold

Cure for colds needs to wiggle while it works

Published in TB and Outbreaks Week, June 21st, 2005

An antiviral compound that wiggles its way into the common cold virus may provide one piece of the solution to halting the infection, say Purdue University scientists.

Using computer simulations, a team of scientists led by Carol B. Post has found the likely reason why a WIN compound - a prototype drug for curing colds - is showing so much promise. The flexible molecule's structure may allow it to shimmy inside the proteins that form the virus' outer shell and alter them to the point where they cannot complete the infection process. An animated video of the computer simulation illustrates some of the results the team describes in its research paper, which appears in...

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