Pulmonary Tuberculosis
NRAMP1 gene variants associated with severe forms of pulmonary tuberculosis
Published in TB and Outbreaks Week, June 21st, 2005
"Although genetic factors may affect susceptibility to tuberculosis, studies that have assessed variants of the natural resistance-associated macrophage protein 1 gene (NRAMP1) and their association with tuberculosis in humans have yielded conflicting results.
"It is likely that NRAMP1 polymorphisms may be associated with progression to severe forms of pulmonary tuberculosis rather than with susceptibility to Mycobacterium tuberculosis infection," scientists in China report.
"To test this possibility, we examined NRAMP1 variants at the INT4 and...
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