Published in TB and Outbreaks Week, June 28th, 2005
"Guinea pigs are often used as an animal model of human TB. However, there are few methods available for pursuing the immunological processes involved in guinea pig TB," reported H. Yamada and associates, Japan Anti-Tuberculosis Association.
"In this study," the researchers explained, "we developed for the first time systematic reverse transcription (RT)-PCR for evaluation of guinea pig mRNA expression. RT-PCR primer sets were newly designed for detection of cytokines and inducible nitric oxide...
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