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HIV/AIDS Risk Factors

Risky sex/amyl nitrite/lack of circumcision associated with HIV seroconversion

Published in TB and Outbreaks Week, July 5th, 2005

Risky sex, amyl nitrite inhalation and lack of circumcision are associated with HIV seroconversion in gay men.

According to recent research from the United States, "Men who have sex with men (MSM) continue to account for the largest number of new HIV infections in the United States, but limited data exist on independent risk factors for infection beyond the early 1990s.

"The HIV Network for Prevention Trials Vaccine Preparedness Study enrolled 3257 MSM in 6 U.S. cities from 1995 to 1997. HIV seroincidence was 1.55 per 100 person-years (95% confidence interval: 1.23-1.95) over 18 months of follow-up."

"On multivariable analysis...

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