SARS Vaccine
RNA interference inhibits SARS-CoV antigen
Published in TB and Outbreaks Week, July 19th, 2005
According to recent research from China, "Severe acute respiratory syndrome (SARS) is an infectious disease caused by SARS-CoV. There are no effective antiviral drugs for SARS although the epidemic of SARS was controlled.
"The aim of this study was to develop an RNAi (RNA interference) approach that specifically targeted the N gene sequence of severe acute respiratory syndrome associated coronavirus (SARS-CoV) by synthesizing short hairpin RNA (shRNA) in vivo, and to assess the inhibitory effect of this shRNA on SARS-CoV N antigen expression."
"The eukaryotic expression plasmid...
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