Cell Biology
New bacterial path for finding iron described
Published in TB and Outbreaks Week, July 26th, 2005
Tuberculosis is a major global pathogen for which there is increasing drug resistance. This iron acquisition mechanism represents a potential new antibiotic target.
Mycobacterium tuberculosis multiplies within endocytic vesicles called phagosomes within macrophages - cells of the immune system - during infection, but nothing was known about how these bacteria found the iron necessary for growth. John Groves and colleagues writing in the August 2005 issue of Nature Chemical...
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