Mycobacterium Tuberculosis
GM-CSF production disruption in lungs affects ability to control MTB infection
Published in TB and Outbreaks Week, August 9th, 2005
According to a recently published study from the United States, "Mice lacking expression of granulocyte macrophage-colony stimulating factor (GM-CSF KO) are unable to contain Mycobacterium tuberculosis (M. tuberculosis) growth and succumb to infection by 35 days following pulmonary challenge.
"GM-CSF KO mice do not express normal levels of the inflammatory cytokine tumor necrosis factor alpha (TNF-alpha) nor the chemokines, regulated on activation, normal T expressed and...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of TB and Outbreaks Week
More Articles from TB and Outbreaks Week
- Mycobacterium Tuberculosis
Fluoroquinolone resistance protein from M. tuberculosis mimics DNA - Mycobacterium Tuberculosis
Nitroimidazopyran PA-824 active against multidrug-resistant MTB - Neisseria Meningitides
Outer membrane vesicle vaccine against serogroup A N. meningitides developed - Sexually Transmitted Disease
Asymptomatic rectal infections support routine STD screening - Hemophilus ducreyi
H. ducreyi dsrA mutant killed by normal human serum initiated by IgM binding - Antimycobacterial Drug Development
Oxadiazolone derivatives have antimycobacterial activity - More from this issue of TB and Outbreaks Week
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
