SARS Vaccine

Epitope mapping of antibodies produced by inactivated SARS isolate reported

Published in TB and Outbreaks Week, August 9th, 2005

Researchers have performed epitope mapping and biological function analysis of antibodies produced by immunization of mice with an inactivated Chinese isolate of severe acute respiratory syndrome-associated coronavirus (SARS-CoV).

According to recent research published in the journal Virology, "Inactivated severe acute respiratory syndrome-associated coronavirus (SARS-CoV) has been tested as a candidate vaccine against the re-emergence of SARS. In order to understand the efficacy and safety of this approach, it is important to know the antibody specificities generated with inactivated SARS-CoV. In the current study, a panel of twelve monoclonal antibodies (mAbs)...

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Source: TB and Outbreaks Week (2005-08-09)

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