Epstein-Barr Virus

HSP90 expression in EBV-infected B cells promotes gammadelta T-cell growth

Published in TB and Outbreaks Week, August 16th, 2005

Heat shock protein 90 expression in Epstein-Barr virus-infected B cells promotes gammadelta T-cell growth.

According to recent research published in the Journal of Virology, "The aim of this study was to elucidate the in vitro response of gammadelta T cells to Epstein-Barr virus (EBV)-infected B cells and to determine whether EBV-induced heat shock proteins (HSPs) might serve as gammadelta T-cell stimulants.

"Cytofluorometric analysis revealed HSP90 cell surface expression in 12% of the EBV-immortalized B-cell population in all four of the B-cell lines tested. HSP27, HSP60, and HSP70 were not detected on the cell surface by cytofluorometry in...

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Source: TB and Outbreaks Week (2005-08-16)

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