HIV/AIDS Epidemic

HIV-1B and C subtypes have different epidemic potentials

Published in TB and Outbreaks Week, August 16th, 2005

The HIV-1B and C subtypes have different epidemic potentials.

"HIV, the cause of AIDS in humans, is characterized by great genetic heterogeneity. In particular, HIV-1 group M subtypes are responsible for most of the infections worldwide. We investigated the demographic history of HIV-1B and HIV-1C subtypes in South Africa and Brazil using both a parametric and a nonparametric approach based on coalescent theory," scientists writing in the Journal of Molecular Evolution report.

"Our results show that although both subtypes are spreading exponentially in Brazil, the HIV-1C growth rate is about twice that of Brazilian HIV-1B or South African...

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Source: TB and Outbreaks Week (2005-08-16)

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