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SARS Coronavirus

Rolling circle amplification is rapid/sensitive for SARS coronavirus detection

Published in TB and Outbreaks Week, August 16th, 2005

The rolling circle amplification method is rapid and sensitive for SARS coronavirus detection.

"The severe acute respiratory syndrome (SARS) epidemic of 2003 was responsible for 774 deaths and caused significant economic damage worldwide. Since July 2003, a number of SARS cases have occurred in China, raising the possibility of future epidemics," scientists in Australia report.

"We describe here a rapid, sensitive, and highly efficient assay for the detection of SARS coronavirus (SARS-CoV) in cultured material and a small number (n=7) of clinical samples.

"Using rolling circle amplification (RCA), we were able to achieve sensitive...

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