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SARS

New treatment against SARS effective in monkeys

Published in TB and Outbreaks Week, September 13th, 2005

A new paper reports that small interfering RNAs, short RNA sequences that can inhibit gene expression, are effective against infection with the severe acute respiratory syndrome (SARS) virus in monkeys.

In 2003, the SARS virus spread through the world, causing lethal pneumonia and lung failure. Since then, the search for therapies against this pathogen has been a very active research field. Now, Patrick Lu and his colleagues at Intradigm Corp., Rockville, Maryland, have shown that siRNA can both prevent the onset of SARS and cure an existing infection in macaques. Their findings appear in the September 2005 issue of Nature Medicine.

The...

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