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Diagnostics

Single-specimen processing for mycobacterial detection sensitive, specific

Published in TB and Outbreaks Week, September 20th, 2005

A single-specimen processing method for the detection of mycobacterium is sensitive and specific.

"The universal sample processing (USP) multipurpose methodology was developed for the diagnosis of tuberculosis (TB) and other mycobacterial diseases by using smear microscopy, culture, and PCR (S. Chakravorty et al. J. Clin. Microbiol. 2005;43:2697).

"Its performance was evaluated in a blinded study of 571 sputa and compared with that of the direct and N-acetyl L-cysteine (NALC)-NaOH methods of smear microscopy and culture," researchers in India report.

"With culture used as the gold standard, USP smear microscopy demonstrated a...

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