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Epstein-Barr Virus

Researchers' findings advance epstein-barr virus research

Published in TB and Outbreaks Week, September 20th, 2005

Investigators in Sweden and the United Kingdom have published new epstein-barr virus data.

Study 1: BV infection induces expression of the ATF-2/c-Jun in B but not B cell type chronic lymphocytic leukaemia cells.

"B cell type chronic lymphocytic leukaemia (B-CLL) cells carry the Epstein-Barr virus (EBV) receptor CD21 and can be infected in vitro with the virus. The infected cells exhibit an unusual EBV program, they express the nuclear proteins but not latent membrane protein 1 (LMP-1).

"Similar cells were encountered in lymphoid tissues of infectious mononucleosis (IM) patients and in lymphoproliferations of immunosuppressed...

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