Typhoid Fever

Vaccine for typhoid and food poisoning possible

Published in TB and Outbreaks Week, September 20th, 2005

Scientists have identified a key molecule used by Salmonella food poisoning bacteria to break into our gut walls, leading to hope for a vaccine.

Salmonella kills millions of people every year and causes a wide variety of illnesses from typhoid fever to food poisoning by using a unique ability to break through the lining in our guts, allowing the bacteria to enter our bodies. Once inside our guts they evade our natural defenses by hijacking protective cells called macrophages, which would normally attack invaders of our bodies.

Scientists from Trinity College Dublin have identified a protein molecule called PagN which Salmonella...

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Source: TB and Outbreaks Week (2005-09-20)

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