Published in TB and Outbreaks Week, September 27th, 2005
According to recent research from the Netherlands, "We have developed a multiplexed and miniaturized TB serological assay with the aim of identifying (combinations of) antigens that maximally discriminate between TB and non-TB patients. It features a microarray accommodating 54 TB antigens, less than 1 microliter serum consumption and an indirect immunofluorescence detection protocol.
"With a panel of 20 TB and 80 non-TB sera we ranked combinations of TB antigens with respect to sensitivity and specificity of TB detection by means of logistic...
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