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Diagnostics

PCR sensitivity low for MTB detection from pleural effusion

Published in TB and Outbreaks Week, October 11th, 2005

The sensitivity of PCR for the detection of Mycobacterium tuberculosis from the pleural effusion is low.

"There is no exact consensus about the usefulness of the Mycobacterium tuberculosis polymerase chain reaction (PCR) testing for the diagnosis of tuberculous pleural effusion because of the diverse PCR methods and the different diagnostic criteria that are described in other studies.

"We analyzed pleural effusion specimens obtained from 111 patients for whom the exclusion of the possibility of tuberculous pleural effusion was necessary," wrote investigators in South Korea.

"We performed M. tuberculosis PCR...

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