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TB and Outbreaks Week

Susan Hasty, Publisher

Table of Contents . . . October 18th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in TB and Outbreaks Week | Other Publications

Dengue Fever Outbreaks - Dengue outbreak characterized by prominent gastrointestinal symptoms

Drug Resistance - Ciprofloxacin failure against TB due to rapid emergence of resistance

Epidemiology - Osteomyelitis/septic arthritis outbreak in children caused by K. kingae

Foot-and-Mouth Disease Outbreaks - Foot-and-mouth disease virus variant responsible for recent outbreaks in India

Respiratory Syncytial Virus Epidemiology - High infectiousness of RSV permits rapid geographic spread of novel variants

Bovine Spongiform Encephalopathy - RT-PCR assay identifies BSE risk material in meat and meat products

Cytomegalovirus Retinitis Prognosis - Detectable plasma CMV load at CMV retinitis diagnosis associated with mortality

Diagnostics - Tuberculosis infection may be prevented by quick DNA testing

Drug Development - Lipophilic antifolate trimetrexate inhibits Trypanosoma cruzi

Drug Development - Monoclonal antibody combination neutralizes natural rabies virus variants

Drug Development - Novel precursors for antimalarial antifolates identified

Drug Development - Secondary metabolites from Chamaedora tepejilote are active against MTB

Drug Safety - Liposomal amphotericin B safe/effective for pediatric visceral leishmaniasis

Epidemiology - Amyloid A amyloidosis associated with familial Mediterranean fever

Epidemiology - Ancestral infection and selection graph reconstruct host virus histories

Epidemiology - Early clinical features of West Nile virus infection are nonspecific

Epidemiology - Surveillance data suggest that preschoolers drive flu epidemics

Epstein Barr Virus - Two distinct cells of origin for EBV-positive and EBV-negative Burkitt lymphomas

Food Safety - High-pressure treatment increases inactivation of bacterial toxins

Genetics & Genomics - Comparative genomics assess significance of emerging Escherichia coli

Genetics & Genomics - Gene functions identified for melanization of Cryptococcus neoformans

HIV/AIDS & Pulmonary Tuberculosis - HIV patients with nonhealing oral lesions should be screened for pulmonary TB

HIV/AIDS Diagnostics - Dried blood spots used for molecular diagnosis and monitoring HIV-1 infection

HIV/AIDS Diagnostics - Genotypic assay detects all HIV-1 protease and reverse transcriptase subtypes

HIV/AIDS Epidemiology - HIV-1 group M isolates are 100-fold-more fit than group 0 or HIV-2 strains

HIV/AIDS Pathogenesis - Mucosal barrier greatly limits SIV infection of cervicovaginal tissues

HIV/AIDS Prevention - African women’s group unveils new campaign to fight AIDS

HIV/AIDS Prevention - HAART suppresses HIV-1 RNA/not DNA in breast milk during pregnancy/postpartum

HIV/AIDS Prognosis - Low CD4 counts before HIV-1 seroconversion do not affect disease progression

HIV/AIDS Superinfection - HIV-1 superinfection is not a common event

HIV/AIDS-Coinfection -  C. gattii serotype C from AIDS patients belongs to rare VGIV genotype

Imaging - Serial chest radiographs necessary to rule out SARS in screening clinic

Immunology -  Schistosoma mansoni analyzed in vitro and in silico, signal peptides studied

Influenza - U.S. NIH grant awarded for development of human vaccine against avian flu

JC Virus Pathogenesis - Sp1 binding sites complete JCV replication cycle in absence of HIV-coinfection

Malaria - Intermittent prophylaxis shown to prevent malaria in infants

Malaria - The best malaria drugs are not being used in Africa

Malaria Risk Factors - Non- and semi-immune pregnant women and their fetuses are at risk for malaria

Measles Vaccine - Measles vaccination effective after household exposure during outbreak

Mycobacterium Tuberculosis - MTB pknH gene deletion confers higher bacillary load during chronic infection

Mycobacterium Tuberculosis - Two-component system found in Mycobacterium tuberculosis

Respiratory Syncytial Virus - Recent studies add new data to respiratory syncytial virus research

SARS - Angiotensin converting enzyme 2 is a crucial SARS coronavirus receptor

SARS - Researchers peg molecular images of protein SARS virus uses to initiate disease

SARS Coronavirus - Findings advance knowledge in SARS coronavirus research

SARS Epidemiology - Inapparent nosocomial SARS coronavirus infection in Vietnam evaluated

Simian Immunodeficiency Virus Infection - CD8+ response after vaginal SIV exposure too little and late to clear infection

Tuberculosis - Training local health workers is found to improve TB control in South Africa

Tuberculosis Diagnosis - TB case detection improved through public-private partnership

Tuberculosis Treatment - Poor patient compliance and duration of TB treatment predict recurrent disease

Tuberculosis Vaccines - Data advance knowledge in tuberculosis vaccines research

Vaccine Development - IL-4 and IL-482 ratio may be marker for pulmonary tuberculosis disease activity

Venezuelan Equine Encephalitis - Envelope glycoprotein mutations mediate VEE amplification and virulence

Virology - Dengue virus NS1 studied, fate of secreted form defined

Virology - Scientists show tick-borne flaviviruses use novel mechanism to evade defenses

West Nile Virus - Immunoassay to detect anti-West Nile virus IgM antibodies developed

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