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Dental Care

Low salivary levels of antimicrobial peptides may contribute to dental caries susceptibility

Published in TB and Outbreaks Week, November 8th, 2005

Low salivary levels of antimicrobial peptides may contribute to dental caries susceptibility.

"Dental caries is a major worldwide oral disease problem in children. Although caries are known to be influenced by dietary factors, the disease results from a bacterial infection; thus, caries susceptibility may be affected by host factors such as salivary antimicrobial peptides," scientists in the United States report.

"This study aimed to determine a possible correlation between caries prevalence in children and salivary concentrations of the antimicrobial peptides human beta-defensin-3 (hBD-3), the cathelicidin LL37, and the alpha-defensins HNP1-3 (a...

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