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SARS

SARS-CoV mutations occur in separate geographic locations and at different times

Published in TB and Outbreaks Week, November 8th, 2005

SARS coronavirus mutations occur in separate geographic locations and at different times.

According to a study from People's Republic of China, "Single nucleotide variations (SNVs) at 5 loci (17564, 21721, 22222, 23823, and 27827) were used to define the molecular epidemiologic characteristics of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) from Beijing patients.

"Five fragments targeted at the SNV loci were amplified directly from clinical samples by using reverse transcription-polymerase chain reaction (RTPCR), before sequencing the amplified products."

"Analyses of 45 sequences obtained from 29 patients...

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