Diagnostics
R. prowazekii multispacer typing discriminates between natural and intentional typhus outbreaks
Published in TB and Outbreaks Week, November 29th, 2005
According to recent research from France, "Currently, there is no tool for typing Rickettsia prowazekii, the causative agent of epidemic typhus, currently considered a potential bioterrorism agent, at the strain level.
"To test if the multispacer typing (MST) method could differentiate strains of R. prowazekii, we amplified and sequenced the 25 most variable intergenic spacers between the R. prowazekii and R. conorii genomes in five strains and 10 body louse amplicons of R. prowazekii from various...
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