HIV/AIDS Transmission
Chorioamnionitis is associated with placental transmission of HIV-1 subtype E
Published in TB and Outbreaks Week, December 6th, 2005
"The frequency and the cellular basis for HIV-1 transmission from mother-to-child in the early gestational period are poorly understood. We compared the placentas of 24 women seropositive for HIV-1 subtype E and who had not received any antiretroviral drugs, to placentas of 25 seronegative women.
"All placentas were obtained during therapeutic abortion at 6-23 weeks gestation. Placentas and fetal organs were examined by routine light microscopy, immunostaining for p24 capsid protein, and in situ PCR to localize which cells were infected with...
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