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Tuberculosis

New TB vaccine enters phase I clinical trial

Published in TB and Outbreaks Week, December 20th, 2005

A phase I clinical trial of a new tuberculosis (TB) vaccine to be administered as a follow-up to the standard initial vaccine has been initiated at the Department of Infectious Diseases at Leiden University Medical Center in the Netherlands and is being supported by the European Union-funded program "TB-VAC."

The Calmette (Bacillus Calmette-Guerin (BCG)) is a live vaccine that, when given to newborns, provides good protection against TB for 10-15 years. However, when the protective effect decreases, yet another BCG vaccination does not provide sufficient TB protection. Therefore, a new type of TB vaccine is needed to address the need of TB protection in the adult...

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