Tuberculosis Pathogenesis
Protein coded by Rv1747 gene required for normal virulent MTB infection
Published in TB and Outbreaks Week, December 20th, 2005
According to recent research from England, "Forkhead-associated (FHA) domains are modular phosphopeptide recognition motifs with a striking preference for phosphothreonine-containing epitopes.
"FHA domains have been best characterized in eukaryotic signaling pathways but have been identified in six proteins in Mycobacterium tuberculosis, the causative organism of tuberculosis."
"One of these, coded by gene Rv1747, is an ABC transporter and the only one to contain two such modules. A deletion mutant of Rv1747 is...
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