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Diagnostics
Real-time NASBA as sensitive as real-time PCR for SARS-CoV detection
January 17th, 2006
A real-time NASBA assay is as sensitive as real-time PCR for the detection of SARS-related coronavirus. "Severe acute respiratory syndrome (SARS) exhibits a high mortality rate and the potential for rapid epidemic spread. Additionally, it has a poorly defined clinical presentation, and no known treatment or prevention methods. Collectively, these factors underscore the need for early diagnosis," investigators in the United States report. "Molecular tests have been developed to detect SARS coronavirus (SARS-CoV) RNA using real time reverse transcription polymerase chain reaction (RT-PCR) with varying levels of sensitivity. However, RNA amplification...
Source: TB & Outbreaks Week (2006-01-17)
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