Drug Resistance
AsnB involved in natural resistance of Mycobacterium smegmatis resistance
Published in TB and Outbreaks Week, March 28th, 2006
According to recent research from Canada, "Mycobacteria are naturally resistant to most common antibiotics and chemotherapeutic agents. The underlying molecular mechanisms are not fully understood."
"In this paper, we describe a hypersensitive mutant of Mycobacterium smegmatis, MS 2-39, which was isolated by screening for transposon insertion mutants of M. smegmatis mc2155 that exhibit increased sensitivity to rifampin, erythromycin, or novobiocin.
"The mutant MS 2-39 exhibited increased sensitivity to all three of the...
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