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Malaria Vaccines

New findings in malaria vaccines described

Published in TB and Outbreaks Week, March 28th, 2006

Data on malaria vaccines are outlined in reports from the United States and Colombia.

Study 1: Antimerozoite surface protein-1 antibodies interfere with Plasmodium falciparum multiplication.

According to a study from Germany, "The 190-kDa merozoite surface protein 1 (MSP-1) of Plasmodium falciparum, an essential component in the parasite's life cycle, is a primary candidate for a malaria vaccine.

"Rabbit antibodies elicited by the heterologously produced MSP-1 processing products p83, p30, p38, and p42, derived from strain 3D7, were analyzed for the potential to inhibit in vitro erythrocyte invasion by the parasite...

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