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Epidemiology

 Escherichia coli O157:H7 mutation rate is locus specific

Published in TB and Outbreaks Week, April 18th, 2006

Escherichia coli O157:H7 mutation rate is locus specific.

"Multilocus variable-number tandem repeat analysis (MLVA) is a validated molecular subtyping method for detecting and evaluating Escherichia coli 0157:117 outbreaks. In a previous study, five outbreaks with a total of 21 isolates were examined by MLVA," scientists in the United States report.

According to A.C. Noller and colleagues at the University of Pittsburgh Graduate School of Public Health, "Nearly 20% of the epidemiologically linked strains were single-locus variants (SLV) of their respective predominant outbreak clone.

"This result prompted an...

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