Published in TB and Outbreaks Week, May 2nd, 2006
Study 1: A mycobacteriophage-based assay rapidly assesses Mycobacterium tuberculosis susceptibility to isoniazid.
"We standardized and assessed the performance of an in-house microtiter assay for determining the susceptibilities of Mycobacterium tuberculosis clinical isolates to isoniazid based on mycobacteriophage amplification technology.
"Seventy isolates (43 resistant and 27 sensitive according to the BACTEC 460 radiometric method and MIC determination) were studied. The isoniazid resistance molecular mechanism was previously...
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