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HIV/AIDS HAART Drug Resistance

HAART drug resistance and HIV clade distributions analyzed among blood donors in Brazil

Published in TB and Outbreaks Week, May 16th, 2006

HAART drug resistance and HIV clade distributions were analyzed among HIV-infected blood donors in Sao Paulo, Brazil.

"We analyzed rates of drug resistance mutations in antiretroviral-naive Sao Paulo blood donors with recently acquired or established HIV-1 infections and characterized clade diversity in this population. Six hundred forty-eight seropositive blood donor specimens were identified at the Blood Center of Sao Paulo between July 1998 and March 2002.

"To discriminate recent infections, samples were subjected to the standardized testing algorithm for recent HIV seroconversion (less-sensitive enzyme immunoassay) testing algorithm," scientists...

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