Anthrax Histopathology
Murine model reproduces human histopathology of anthrax
Published in TB and Outbreaks Week, May 23rd, 2006
"Systemic anthrax infection is usually fatal even with optimal medical care. Further insights into anthrax pathogenesis are therefore urgently needed to develop more effective therapies. Animal models that reproduce human disease will facilitate this research," scientists in the United States report.
According to the authors, "Here, we describe the detailed histopathology of systemic anthrax infection in A/J mice infected with Bacillus anthracis Sterne, a strain with reduced virulence for humans."
"Subcutaneous infection leads to systemic disease with...
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