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HIV/AIDS Epidemiology

HIV-1 subtype B and F infections evolving at similar rate over time in Brazil

Published in TB and Outbreaks Week, May 30th, 2006

HIV-1 subtype B and F infections in Brazil are evolving at a similar rate over time.

In a recent report, researchers in Brazil conducted a study to "reconstruct the onset date of the HIV-1 B and F epidemics in Brazil based on virus diversification over time. We studied HIV-1 env V3 sequences (210nt) with a known sampling year isolated from HIV-1 positive patients from Brazil between 1989 and 1997: 101 subtype B sequences and 41 subtype F sequences.

"HIV-1 V3 env sequences were grouped by year of collection and the relationship between the sampling years of HIV-1 sequences and their genetic distance to the reconstructed common ancestor...

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