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HIV/AIDS Diagnostics

P24 antigen accurately monitors HAART in pediatric HIV-1 infection

Published in TB and Outbreaks Week, June 13th, 2006

The p24 antigen test accurately monitors HAART in pediatric HIV-1 infection.

"Worldwide, 700,000 infants are infected annually by HIV-1, most of them in resource-limited settings. Care for these children requires simple, inexpensive tests," investigators in Switzerland report.

According to M.W. Brinkhof and colleagues at the University of Zurich, "We have evaluated HIV-1 p24 antigen for antiretroviral treatment (ART) monitoring in children. p24 by boosted enzyme-linked immunosorbent assay of heated plasma and HIV-1 RNA were measured prospectively in 24 HIV-1-infected children receiving ART.

"p24 and HIV-1 RNA concentrations and...

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