Published in TB and Outbreaks Week, June 13th, 2006
"The paucibacillary nature of the cerebrospinal fluid (CSF) has been a major obstacle in the diagnosis of human tuberculous meningitis (TBM). This study shows that with molecular techniques direct precise determination to the species level of mycobacterial pathogens can be made," researchers in India report.
According to the authors, "The present report describes the utility of a nested PCR (N-PCR) assay in detecting M. tuberculosis and M. bovis in human CSF. In 2.8% (6/212) of the samples, M. tuberculosis was detected, and in 17%...
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