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Cytomegalovirus Therapy

Leflunomide is possible alternative for gangciclovir sensitive and resistant CMV infection

Published in TB and Outbreaks Week, July 4th, 2006

Leflunomide is a possible alternative for gangciclovir sensitive and resistant cytomegalovirus infection.

"The search for newer more cost effective treatments for infectious diseases remains a challenge. Cytomegalovirus (CMV) infection, which is especially common in the immunosuppressed, is an important challenge for treating physicians," researchers in India report.

According to the authors, "Gangciclovir's cost is a major hurdle in developing countries. Leflunomide is cheaper and is easily given orally. It works by a novel mechanism inhibiting virion assembly.

"It also has immunosuppressive properties," and has "been shown to be...

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